Transdermal Patch – Relief 1:1 CBD:THC

Cannabis Extract
40 Review(s)

Mary’s Medicinals Relief Transdermal Patch, with a 1:1 CBD:THC ratio, is designed to promote relief from common aches and pains in your daily life. Our Everyday Relief products are formulated with natural ingredients that provide systemic relief from daily stressors. Winner of the 2023 Michigan and SoCal High Times Cups, Mary’s Relief Transdermal Patch is sure to be a winner in your book as well.

Mary’s award-winning transdermal patches come from our commitment to accurate dosing through an advanced delivery method. The discreet 2×2” squares simply adhere to any veinous part of the skin like the inner wrist of top of the foot for 8-12 hours of effect. Heat, sweat and water-resistant, Mary’s patches can be simply and accurately micro-dosed by cutting them down.


Available in CBD, 1:1 CBD:THC, CBG, CBN, THCa, Indica and Sativa.

Mary’s Patches can easily be micro-dosed by cutting them down into halves or quarters.
1:1 (10mg CBD:10mg THC) CA, CO, MI, MO, NV, OH, VT, IL, Canada


Tips for Use
  • Remove the plastic liner and press the patch firmly onto clean, dry skin.
  • Apply the patch to venous areas, like the wrist or top of your foot.
  • Our patches are sweat and water-resistant.
  • Mary’s Patches can easily be micro-dosed by cutting them down into halves or quarters. 8-to-12-hour time release remains the same regardless of dosage.
  • Onset: 15-30 mins
  • When not wearing a patch, keep the area moisturized. This will ensure optimal performance when using patches.

How To Use

The patch is most effective when applied to a veinous part of the body, like the top of the foot or inner wrist. Cleanse and dry skin prior to application. Remove plastic liner and press patch firmly onto skin. Effects last up to 12 hours. Patch should be worn continuously.


Cannabis extract, eucalyptus, naturally derived terpenes.  


California, Colorado, Michigan, Missouri, Nevada, Ohio, Vermont, Illinois, Canada


  1. Rae

    Using this patch was the first time. I absolutely love it.

  2. Jan Hill

    The patch at $10 for daily use is I believe out of range for most. If it’s a 24/7 need that works out to 20×30=$600. Impossible to meet Yet another for the top 20%.

  3. Terrance Cox

    Great product. Always get a couple when I go to the dispensary. I use the THC/CBD. If these could be cut I’d be even happier! 😃

  4. Amber Griffin

    I buy the patient kit of this patch every month. I wear one in the top of my foot everyday. If I am wearing my patch everyday then I am functional and can go to work and feel normal all day. When I don’t wear a patch I drag my right leg and foot. It is truly amazing how much this patch has helped me in the last year. I literally can’t go without one anymore. Thank you for making a product that helps make me function all day long. I can’t put into words how much I truly appreciate Mary’s and this 1:1 patch.

  5. Lisa Haynes

    I cut mine in 1/2 and it’s just enough

  6. Amanda Richardson

    Mary’s 1:1 patch is a must have product for anyone. I overlap the application of patches for maximum effect. Love this product!!!


    You can cut them, but I used the whole patch 1:1 CBD: THC I used on my wrist first and then changed to the top of my foot and it was a better response. I definitely will use more. Trying the gel tomorrow. I like Marys’ products she has been around and doing this for a long time and has grown tremendously with the formulas and product offerings. I highly rec. you give her products a try. Natural healing is the best. A great alternative to narcotics. Autoimmune Warrior, thank you

  8. Kara

    I would give this 1,000 stars!

  9. Andrea White

    Love this it is the best for pain relief!!! However it sells out everywhere. Please let me know how to purchase it. And where!!!

  10. Donna Gundlach

    Loved this product

  11. Lisa Brown

    I live in Washington State and am being told you’re out of business. Your patches help my fibromyalgia. Help, where can I purchase them?

  12. Zoe T Orsborne

    I rely on this daily. It’s just the right balance for arthritis and shingle pain. My only complaint is that it is in short supply which means I frequently go without.

  13. Jennifer Larsson

    I have herniated discs in my lower lumbar along with several other back conditions that cause excruciating pain. I am in physical therapy and struggle to complete the exercises because even the slightest movement sends electrical type pain down my legs. After being unable to walk, use the bathroom or shower for two weeks with out assistance I decided to try something new for pain relief. I bought this per suggestion of a friend. I cut this patch into 4s as this was my first interaction with cbd/thc products. Within 10 minutes I began to feel immediate relief. I was able to do so many things I hadn’t been able to do in such a long time. The pain I had been feeling which was at a 10 was now a 3. I felt like I had some of my independence back. I will be making a large purchase in the foreseeable future as I hope this will decrease my pain enough that I can actually complete my therapy, interact with my family… Live. Thank you SOOOO much for such an amazing product!

  14. Kathy

    I love the 1-1 patches but I can not find them anymore. Where can I get them

  15. Eric Wischman

    Very good – helped my old age problems

  16. Toni Briggs

    I use the CBD:THC. 1 : 1 It works miracles on my pain, neck, back, knees, hips and feet. Finally relief. But now I can’t find them anymore. Any suggestions?

  17. Emily Peters

    I’d honestly give it a 5 however upon carefully removing it last week it took a chunk of skin with it and it has yet to heal. I am going to try this product again because I liked it that much! however if this repeats I will unfortunately have to not use this product that helped.

  18. Tara

    Love these! I often cut them in half and use 1/2 at a time – works great!

  19. Jamie

    These are the best things I have EVER found for my period cramps. After having children, the cramps are way worse now and this has been a much better alternative than using advil/tylenol/ibuprofen. I highly recommend. They do not make you high whatsoever.

  20. Toni Briggs

    I love this 1:1 patch. It has helped me with my overall pain. The only problem I have is getting it as the dispensaries say they can’t order, they get what they get. I guess it’s not a big enough seller to worry about. I use 1 everyday and am miserable without it. I definitely recommend this patch if you don’t want a high. It just does its thing without side effects. I buy them out when I can find them.

  21. sherri squire

    I am absolutely shocked.. this product is amazing..

  22. Mary Olson

    Excellant product, I have cut them and used at night, would reccomend!

  23. John Nelson

    It’s great, I’m in the grocery business and have a lot of physical activity and I’m not so young anymore. Love it I recommend this to my friends.

  24. Lana Syriani

    Amazing product!! It’s truly the one magical product that works!

  25. Samantha D.

    Believe it or not, after taking this patch, it’s the best my wife has felt in over a month. Thank you!!!

  26. Janet Kendle

    They are pricey for me but I bought whatever I could afford on a weekly basis . I used these patches for approximately 8 weeks until my dispensary ran out of them. They have been out of them for quite a while now and you cannot imagine my disappointment as I cannot seem to locate these patches anywhere. The biggest disappointment in my life.

  27. Crystal

    Absolutely love these patches, I grab some every time I find them available (which unfortunately isn’t often). These stay one the entire intended amount of time, are discreet, and do not cause an overwhelming “high” feeling.

  28. Frankie

    Absolutely love the 1:1 thc cbd only problem is I can’t find dispensaries around me are always out of stock. I deal with constant pain and anxiety so have to watch the thc level and the patch was perfect.

  29. Jordan

    I loved the effects but sadly the adhesive made me break out. I have a latex allergy and sensitivity to adhesive. Maybe you could put little warning on it for others. I look forward to trying your other topicals! Great product for sure

  30. Amy

    My husband is a combat veteran with significant injuries from multiple explosions. He has been treated with opiates for his pain for well over a decade. We tried a patch and he woke up without 8 out of 10 pain for the first time in over a decade. The idea of not being tied to pain killers for the rest of his life is actually a reality.

  31. Rebecca

    I live In Illinois and I suffer with chronic pain and I’d love to try these products

  32. Jose

    The patches are awesome I was on my normal sense all the time I was wearing it and got what I was looking for no pain

  33. Jose

    I had the CBD THC patch

  34. Mandy

    I use this particular patch for period cramps, and though they are not gone completely, they are minimized drastically to the point I can get through my usually very painful period with very little issue. Thank you!

  35. MaryKendalyne

    The patches are excellent for pain relief however they’re so expensive that you can’t afford to pay for them out of pocket.

  36. Sherry

    Life changing. I have all over chronic pain. These patches allow me to function normally. Due to the cost, I do save them for very bad pain days. But they are absolutely fantastic. 10/10.

  37. Penelope Curtis

    I love this product how can I become a representative every person I run into that has an issue with pain I recommend it and I sometimes I even volunteer and buy it for them and it has been nothing but rave reviews. Excellent job to the developers I am so serious how can I become a representative for your company this product is outstanding.

  38. John cook

    They work. Difficult to find.

  39. Emilio

    I have Perferal Neuropathy. I can tell the difference when as suggested I place them off the upper part of my left foot. I have a dropped foot on my left leg. It helps.

  40. Hallie J

    This is my second time trying a Mary’s patch and its given me relief for period cramps and in this moment, a strain in my back. You can literally feel the terpenes in your body.

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