Each Gel Pen uses our unique child-safe dosing mechanism. Simply rotate the top portion of the pen counter-clockwise to unlock the child safety mechanism, and turn in the opposite direction to lock it after dispensing. To dispense, push down on the top of the pen. The tip will dispense 2mg of gel per click. Rub gel onto a veinous area of the body, such as your wrist, ankle or top of the foot.